Middlesex is a town in Yates County, New York, USA. The population was 1,495 at the 2010 census. The name originates from a historic region of the UK.
As of the census of 2000, there were 1,345 people, 521 households, and 376 families residing in the town. The population density was 43.6 people per square mile (16.8/km²). There were 732 housing units at an average density of 23.7 per square mile (9.2/km²). The racial makeup of the town was 98.74% White, 0.37% African American, 0.15% Native American, 0.15% Asian, 0.15% from other races, and 0.45% from two or more races. Hispanic or Latino of any race were 0.22% of the population. On a side note it is safe to say that cattle outnumber people at least 4 to 1.
There were 521 households out of which 33.0% had children under the age of 18 living with them, 59.7% were married couples living together, 8.1% had a female householder with no husband present, and 27.8% were non-families. 22.3% of all households were made up of individuals and 10.6% had someone living alone who was 65 years of age or older. The average household size was 2.52 and the average family size was 2.91.
In the town, the population was spread out with 25.9% under the age of 18, 6.3% from 18 to 24, 25.2% from 25 to 44, 29.0% from 45 to 64, and 13.5% who were 65 years of age or older. The median age was 41 years. For every 100 females, there were 100.7 males. For every 100 females age 18 and over, there were 98.8 males.
The median income for a household in the town was $43,618, and the median income for a family was $47,763. Males had a median income of $34,464 versus $23,676 for females. The per capita income for the town was $21,241. About 3.4% of families and 6.6% of the population were below the poverty line, including 7.3% of those under age 18 and 9.4% of those age 65 or over.